Hangzhou Panyu Chemical Co.,Ltd--Fosinopril

Products

Fosinopril

Product Name: Fosinopril

Synonyms: 4-Cyclohexyl-1-[2-[(2-methyl-1-propanoyloxy-propoxy)-(4-phenylbutyl)phosphoryl]acetyl]

CAS No.: 98048-97-6

Molecular Formula: C₃₀H₄₆NO₇P

Molecular Weight: 563.66

Molecular Structure:

Description:

Fosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-convertingenzyme (ACE) inhibitor class of medications. It is rapidly hydrolyzed to fosinoprilat, its principleactive metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component ofthe renin-angiotensin-aldosterone system (RAAS).

Application:

Fosinopril is used for treating high blood pressure alone or with other medicines. It is used along with other medicines to manage heart failure. It may also be used for other conditions as determined by your doctor.

Fosinopril is an angiotensin-converting enzyme (ACE) inhibitor. It works by relaxing blood vessels. This helps to lower blood pressure.

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3.R&D use in accordance with (1) 35 USC 271(e)+A13(1) in the U.S.; (2) Section 69.1 of Japanese Patent Law in Japan; (3) Section 11, No. 2 of the German Patent Act of 1981 in Germany; (iv) Section 60, Paragraph 5b of the U.K. Patents Act of 1977 in the U.K.; (4) Sections 55.2(1) and 55.2(6) and other common law exemptions of Canadian patent law; (5) Section 68B of the Patents Act of 1953 in New Zealand together with the amendment of same by the Statutes Amendment Bill of 2002; (6) such related legislation and/or case law as may be or become applicable in the aforementioned countries; and (7) such similar laws and rules as may apply in various other countries.